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| カタログ番号 | HW778014 | ||||||||
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| 説明 |
Anti-MYH9 Polyclonal Antibody (HW778014) is a rabbit polyclonal antibody detecting MYH9 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MYH9 (Glu1740-Glu1960). | ||||||||
| ターゲット | NMMHC-IIA, Non-muscle myosin heavy chain IIa, Cellular myosin heavy chain, type A, Myosin heavy chain 9, NMMHC II-a, Non-muscle myosin heavy chain A, Myosin-9, MYH9, NMMHC-A, Myosin heavy chain, non-muscle IIa | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P35579 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Myosin-9 (MYH9) is a ~226 kDa protein. Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. 1. Li, ZH. et al. (2006) Cancer research 66, 5173-80. PMID: 16707441 2. Betapudi, V. (2010) PloS one 5, e8560. PMID: 20052411 | ||||||||
| 注意事項 | For research use only. |
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