

| Número de catálogo | JN891043 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Neisseria meningitidis | ||||
| Aplicaciones | ELISA, SPR | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG | ||||
| ID de clon | 12E1# | ||||
| Objetivo | C2 fragment, GNA2132, Genome-derived Neisseria antigen 2132, NHBA, Neisserial heparin binding antigen, gna2132, nhba | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q9JPP1 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Neisserial heparin binding antigen is a ~44 kDa protein. A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds human cells, heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate, heparin and ganglioside GT3. Binds DNA non-specifically. 1. Maritan, M. et al. (2018) PloS one 13, e0201922. PMID: 30133484 | ||||
| Nota | For research use only |



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