

| Numéro de catalogue | JN891043 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Neisseria meningitidis | ||||
| Applications | ELISA, SPR | ||||
| Espèce hôte | Human | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG | ||||
| ID de clone | 12E1# | ||||
| Cible | C2 fragment, GNA2132, Genome-derived Neisseria antigen 2132, NHBA, Neisserial heparin binding antigen, gna2132, nhba | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q9JPP1 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Neisserial heparin binding antigen is a ~44 kDa protein. A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds human cells, heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate, heparin and ganglioside GT3. Binds DNA non-specifically. 1. Maritan, M. et al. (2018) PloS one 13, e0201922. PMID: 30133484 | ||||
| Note | For research use only |



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