Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (5H2) (JN891033)

Name: Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (5H2)
Brand: abinScience
SKU: JN891033
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

JN891033

Reactividad de especies

Neisseria meningitidis

Aplicaciones

ELISA, SPR

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

ID de clon

5H2

Objetivo

nhba, gna2132, Heparin binding protein, Neisserial heparin binding antigen, Genome-derived neisserial antigen 2132, Putative lipoprotein GNA2132, NHBA

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9JPP1

RRID

Anti-Neisseria meningitidis NHBA/Dextranase Antibody (5H2) (abinScience Cat# JN891033, RRID:AB_3727794)
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Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Neisserial heparin binding antigen (NHBA/Dextranase) is a ~44 kDa protein. A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds human cells, heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate, heparin and ganglioside GT3. Binds DNA non-specifically.

1. Maritan, M. et al. (2018) PloS one 13, e0201922. PMID: 30133484

Nota

For research use only.

Imágenes

Bioactivity

Detects Neisseria meningitidis NHBA/Dextranase in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Neisseria meningitidis NHBA/Dextranase Antibody (5H2).
Western blot

Western blot analysis was performed using anti-Neisseria meningitidis NHBA/Dextranase monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant Neisseria meningitidis NHBA (Catalog No: JN891012)
Lane 2: negative control

Referencias

Datasheet

Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (5H2).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo