Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (12E1#) (JN891043)

Name: Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (12E1#)
Brand: abinScience
SKU: JN891043
Price: 191 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

JN891043

Species reactivity

Neisseria meningitidis

Applications

ELISA, SPR

Host species

Human

Isotype

IgG

Clone ID

12E1#

Clonality

Monoclonal

Target

C2 fragment, GNA2132, Genome-derived Neisseria antigen 2132, NHBA, Neisserial heparin binding antigen, gna2132, nhba

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9JPP1

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Neisserial heparin binding antigen is a ~44 kDa protein. A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds human cells, heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate, heparin and ganglioside GT3. Binds DNA non-specifically.

1. Maritan, M. et al. (2018) PloS one 13, e0201922. PMID: 30133484

Note

For research use only

Images

References

Datasheet

Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (12E1#).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Neisseria meningitidis NHBA/Dextranase Recombinant Antibody (12E1#) (JN891043)

Overview

Images

References

Datasheet

SDS

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