Anti-Porcine CD163 Recombinant Antibody (2G01) (SV831023)

Name: Anti-Porcine CD163 Recombinant Antibody (2G01)
Brand: abinScience
SKU: SV831023
Price: 126 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

SV831023

Reactivité des espèces

Porcine

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

VHH-mFc (IgG2a)

ID de clone

2G01

Cible

Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163, CD163, M130

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q2VL90

RRID

Anti-Pig CD163 Antibody (2G01) (abinScience Cat# SV831023, RRID:AB_3729193)
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Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).

Note

For research use only.

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