Anti-Porcine CD163 Recombinant Antibody (2A10) (SV831013)

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100ug
1mg

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Datasheet
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Overview

Catalog No.

SV831013

Description

Anti-Pig CD163 Antibody (2A10) [2A10] (SV831013) is a mouse monoclonal antibody detecting CD163 in ELISA. Suitable for Pig.

Species reactivity

Pig

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

2A10

Clonality

Monoclonal

Target

Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163, CD163, M130

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q2VL90

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).

Note

For research use only.

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