Anti-Porcine CD163 Recombinant Antibody (2G01) (SV831023)

Name: Anti-Porcine CD163 Recombinant Antibody (2G01)
Brand: abinScience
SKU: SV831023
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

SV831023

Species reactivity

Porcine

Applications

ELISA

Host species

Mouse

Isotype

VHH-mFc (IgG2a)

Clone ID

2G01

Clonality

Monoclonal

Target

Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163, CD163, M130

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q2VL90

RRID

Anti-Pig CD163 Antibody (2G01) (abinScience Cat# SV831023, RRID:AB_3729193)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).

Note

For research use only.

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