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| カタログ番号 | HT107014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-QSOX1 Polyclonal Antibody (HT107014) is a rabbit polyclonal antibody detecting QSOX1 in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human QSOX1 (Ser37-Ala181). | ||||||||
| ターゲット | QSOX1, Sulfhydryl oxidase 1, hQSOX, Quiescin Q6, QSCN6 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O00391 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sulfhydryl oxidase 1 (QSOX1) is a ~82 kDa protein. Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. 1. Chakravarthi, S. et al. (2007) The Biochemical journal 404, 403-11. PMID: 17331072 2. Heckler, EJ. et al. (2008) Biochemistry 47, 4955-63. PMID: 18393449 3. Ilani, T. et al. (2013) Science (New York, N.Y.) 341, 74-6. PMID: 23704371 4. Grossman, I. et al. (2013) Journal of molecular biology 425, 4366-78. PMID: 23867277 5. Javitt, G. et al. (2019) Protein science : a publication of the Protein Society 28, 228-238. PMID: 30367560 6. Alon, A. et al. (2012) Nature 488, 414-8. PMID: 22801504 | ||||||||
| 注意事項 | For research use only. |
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