

| Catalog No. | HT107013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1497 | ||||
| Clonality | Monoclonal | ||||
| Target | QSOX1, Sulfhydryl oxidase 1, hQSOX, Quiescin Q6, QSCN6 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | O00391 | ||||
| RRID | Anti-Human QSOX1 Antibody (SAA1497) (abinScience Cat# HT107013, RRID:AB_3727258) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Sulfhydryl oxidase 1 (QSOX1) is a ~82 kDa protein. Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. 1. Chakravarthi, S. et al. (2007) The Biochemical journal 404, 403-11. PMID: 17331072 2. Heckler, EJ. et al. (2008) Biochemistry 47, 4955-63. PMID: 18393449 3. Ilani, T. et al. (2013) Science (New York, N.Y.) 341, 74-6. PMID: 23704371 4. Grossman, I. et al. (2013) Journal of molecular biology 425, 4366-78. PMID: 23867277 5. Javitt, G. et al. (2019) Protein science : a publication of the Protein Society 28, 228-238. PMID: 30367560 6. Alon, A. et al. (2012) Nature 488, 414-8. PMID: 22801504 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human QSOX1 Antibody (SAA1497).
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