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Anti-Human QSOX1 Recombinant Antibody (SAA1497) (HT107013)

Anti-Human QSOX1 Recombinant Antibody (SAA1497)
Anti-Human QSOX1 Recombinant Antibody (SAA1497)
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Overview
Catalog No.HT107013
Description
Anti-Human QSOX1 Recombinant Antibody (SAA1497) (HT107013) is a mouse monoclonal antibody detecting QSOX1 in ELISA. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a, kappa
Clone IDSAA1497
Target QSOX1, Sulfhydryl oxidase 1, hQSOX, Quiescin Q6, QSCN6
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O00391
RRID Anti-Human QSOX1 Antibody (SAA1497) (abinScience Cat# HT107013, RRID:AB_3727258)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Sulfhydryl oxidase 1 (QSOX1) is a ~82 kDa protein. Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.

1. Chakravarthi, S. et al. (2007) The Biochemical journal 404, 403-11. PMID: 17331072
2. Heckler, EJ. et al. (2008) Biochemistry 47, 4955-63. PMID: 18393449
3. Ilani, T. et al. (2013) Science (New York, N.Y.) 341, 74-6. PMID: 23704371
4. Grossman, I. et al. (2013) Journal of molecular biology 425, 4366-78. PMID: 23867277
5. Javitt, G. et al. (2019) Protein science : a publication of the Protein Society 28, 228-238. PMID: 30367560
6. Alon, A. et al. (2012) Nature 488, 414-8. PMID: 22801504
Note For research use only.
Images
  • Anti-Human QSOX1 Recombinant Antibody (SAA1497)

    SDS-PAGE

    SDS-PAGE for Anti-Human QSOX1 Antibody (SAA1497).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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