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Anti-QSOX1 Polyclonal Antibody (HT107014)

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Overview
Catalog No.HT107014
Description
Anti-QSOX1 Polyclonal Antibody (HT107014) is a rabbit polyclonal antibody detecting QSOX1 in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human QSOX1 (Ser37-Ala181).
Target QSOX1, Sulfhydryl oxidase 1, hQSOX, Quiescin Q6, QSCN6
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession O00391
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sulfhydryl oxidase 1 (QSOX1) is a ~82 kDa protein. Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.

1. Chakravarthi, S. et al. (2007) The Biochemical journal 404, 403-11. PMID: 17331072
2. Heckler, EJ. et al. (2008) Biochemistry 47, 4955-63. PMID: 18393449
3. Ilani, T. et al. (2013) Science (New York, N.Y.) 341, 74-6. PMID: 23704371
4. Grossman, I. et al. (2013) Journal of molecular biology 425, 4366-78. PMID: 23867277
5. Javitt, G. et al. (2019) Protein science : a publication of the Protein Society 28, 228-238. PMID: 30367560
6. Alon, A. et al. (2012) Nature 488, 414-8. PMID: 22801504
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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