Anti-Sarilumab Neutralizing Antibody ELISA kit (AY583528)

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参考文献
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カタログ番号	AY583528
説明	Anti-Sarilumab Neutralizing Antibody ELISA kit (AY583528) — Quantitative sandwich ELISA for Anti-Sarilumab Neutralizing Antibody. Sample: Plasma, Serum. Range: 15.625-1, 000 ng/ml. Highlights ●Sandwich Format — High specificity, reliable quantification. ●Ready-to-Use — Complete kit with pre-coated plates included.
サンプルタイプ	Plasma, Serum
レンジ	15.625-1, 000 ng/ml
アクセッション番号	P08887
アプリケーション	ELISA
検出方法	Colorimetric
アッセイタイプ	Quantitative
回収率	80-120%
発送	2-8 ℃
安定性と保存	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
仕様	Sarilumab
別名	REGN88, SAR153191, 1189541-98-7
背景	Interleukin-6 receptor subunit alpha (Sarilumab) is a ~51 kDa protein. Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. 1. Larsen, JV. et al. (2017) Molecular and cellular biology 37. PMID: 28265003 2. Kang, S. et al. (2019) Immunity 50, 1007-1023. PMID: 30995492 3. Spencer, S. et al. (2019) The Journal of experimental medicine 216, 1986-1998. PMID: 31235509
注意事項	For Research Use Only.