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Anti-SEC11A Polyclonal Antibody (HX979014)

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概要
カタログ番号HX979014
説明
Anti-SEC11A Polyclonal Antibody (HX979014) is a rabbit polyclonal antibody detecting SEC11A in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human SEC11A (Met1-Glu179).
ターゲット Microsomal signal peptidase 18 kDa subunit, Endopeptidase SP18, SPCS4A, Signal peptidase complex catalytic subunit SEC11A, SEC11A, SPase 18 kDa subunit, SEC11-like protein 1, SEC11 homolog A, SPC18, SEC11L1
精製 Purified by antigen affinity column.
アクセッション番号 P67812
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Signal peptidase complex catalytic subunit SEC11A is a ~20 kDa protein. Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.

1. Liaci, AM. et al. (2021) Molecular cell 81, 3934-3948.e11. PMID: 34388369
注意事項 For research use only.
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参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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