Anti-SERPINE1/PAI-1 Polyclonal Antibody (HY185014)

Name: Anti-SERPINE1/PAI-1 Polyclonal Antibody
Brand: abinScience
SKU: HY185014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HY185014

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SERPINE1/PAI-1 (Gly21-Pro402).

Cible

PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1

Purification

Purified by antigen affinity column.

Numéro d'accès

P05121

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.

1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774

2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461

3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516

4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454

5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150

6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705

7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579

8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821

9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027

10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142

Note

For research use only.

Images

Reférences

Fiche technique

Anti-SERPINE1/PAI-1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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