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| カタログ番号 | HY185014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SERPINE1/PAI-1 (Gly21-Pro402). | ||||||||
| ターゲット | PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P05121 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. 1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774 2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461 3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516 4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454 5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150 6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705 7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579 8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821 9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027 10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142 | ||||||||
| 注意事項 | For research use only. |
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