

| Número de catálogo | HY328045 |
|---|---|
| Descripción |
Anti-Siltuximab Neutralizing Antibody (1A456) [1A456] (HY328045) is a mouse monoclonal antibody in ELISA.
|
| Reactividad de especies | General |
| Aplicaciones | ELISA |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1 |
| ID de clon | 1A456 |
| Inmunógeno | E. coli - derived recombinant protein. |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | CAS: 541502-14-1 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). |
| Nota | For research use only. |

SDS-PAGE for Anti-Siltuximab Neutralizing Antibody (1A456)




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