Siltuximab ELISA Kit (DY328058)

Overview

Catalog No.	DY328058
Description	Siltuximab ELISA Kit (DY328058) — Quantitative. Sample: Plasma, Serum. Range: 1.56 - 100 ng/mL. Sensitivity: 0.25 ng/mL. Highlights ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with all essential reagents included.
Sample type	Serum, plasma, and other biological fluid samples
Sensitivity	24.57 ng/mL
Range	78.13 - 5,000 ng/mL
Species reactivity	Human
Target	IL6
Accession	P05231
Applications	ELISA
Detection method	Colorimetric
Assay type	Sandwich
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Background	Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For research use only

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Concentration

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Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Overview