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| カタログ番号 | HY328045 |
|---|---|
| 説明 |
Anti-Siltuximab Neutralizing Antibody (1A456) [1A456] (HY328045) is a mouse monoclonal antibody in ELISA.
|
| 種反応性 | General |
| アプリケーション | ELISA |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1 |
| クローンID | 1A456 |
| 免疫原 | E. coli - derived recombinant protein. |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | CAS: 541502-14-1 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Siltuximab Neutralizing Antibody (1A456)
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