Anti-SNRPD1 Polyclonal Antibody (HX906014)

Name: Anti-SNRPD1 Polyclonal Antibody
Brand: abinScience
SKU: HX906014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HX906014

説明

Anti-SNRPD1 Polyclonal Antibody (HX906014) is a rabbit polyclonal antibody detecting SNRPD1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human SNRPD1 (Met1-Arg119).

ターゲット

Sm-D1, Small nuclear ribonucleoprotein Sm D1, SNRPD1, Sm-D autoantigen, snRNP core protein D1

精製

Purified by antigen affinity column.

アクセッション番号

P62314

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Small nuclear ribonucleoprotein Sm D1 (SNRPD1) is a ~13 kDa protein. Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638

2. Chari, A. et al. (2008) Cell 135, 497-509. PMID: 18984161

3. Pomeranz Krummel, DA. et al. (2009) Nature 458, 475-80. PMID: 19325628

4. Grimm, C. et al. (2013) Molecular cell 49, 692-703. PMID: 23333303

5. Kondo, Y. et al. (2015) eLife 4. PMID: 25555158

6. Agafonov, DE. et al. (2016) Science (New York, N.Y.) 351, 1416-20. PMID: 26912367

7. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

8. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770

9. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166

10. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-SNRPD1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-SNRPD1 Polyclonal Antibody (HX906014)

概要

イメージ

参考文献

データシート

SDS