Human SNRPD1 Recombinant Protein (N-GST & C-His) (HX906022)

Name: Human SNRPD1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HX906022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HX906022
Description	Recombinant Human SNRPD1 Protein, N-GST & C-His (HX906022) expressed in E. coli, spanning Lys2-Val87. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P62314
Protein length	Lys2-Val87
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	37.89 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	SNRPD1, Sm-D autoantigen, Sm-D1, Small nuclear ribonucleoprotein Sm D1, snRNP core protein D1
Background	Small nuclear ribonucleoprotein Sm D1 is a ~13 kDa protein. Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Chari, A. et al. (2008) Cell 135, 497-509. PMID: 18984161 3. Pomeranz Krummel, DA. et al. (2009) Nature 458, 475-80. PMID: 19325628 4. Grimm, C. et al. (2013) Molecular cell 49, 692-703. PMID: 23333303 5. Kondo, Y. et al. (2015) eLife 4. PMID: 25555158 6. Agafonov, DE. et al. (2016) Science (New York, N.Y.) 351, 1416-20. PMID: 26912367 7. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 8. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 9. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 10. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006
Note	For research use only

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Human SNRPD1 Recombinant Protein (N-GST & C-His).pdf

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Human SNRPD1 Recombinant Protein (N-GST & C-His) (HX906022)

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