中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | JN998043 | ||||
|---|---|---|---|---|---|
| 種反応性 | Staphylococcus aureus | ||||
| アプリケーション | ELISA, Neutralization, SPR | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a | ||||
| クローンID | 2A3.1 | ||||
| ターゲット | hly, hla, Alpha-hemolysin, Alpha-toxin, Alpha-HL, AT, Staphylococcus aureus, Staphylococcus aureus (strain NCTC 8325 / PS 47) | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P09616, Q2G1X0 | ||||
| RRID | Anti-Staphylococcus aureus Alpha-toxin/hly/AT Antibody (2A3.1) (abinScience Cat# JN998043, RRID:AB_3729028) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Staphylococcus aureus Alpha-toxin/hly/AT Antibody (2A3.1)
Western blot analysis was performed using anti-a1AT/Serpin A1/SERPINA1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human a1AT/Serpin A1/SERPINA1 (Catalog No: HF638012)
Lane 2: negative control
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
