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Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), FITC (JN856117)

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Vista general
Número de catálogoJN856117
Reactividad de especiesStaphylococcus aureus
AplicacionesELISA, FCM, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a
ID de clonSAA1452
ConjugaciónFITC
Objetivo spa, Immunoglobulin G-binding protein A, Staphylococcal protein A
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC
Número de acceso P38507
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Immunoglobulin G-binding protein A (SPA) is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.

Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Concentration
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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