Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), APC (JN856137)

Name: Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), APC
Brand: abinScience
SKU: JN856137
Price: 256 USD
Availability: InStock

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Overview

Catalog No.	JN856137
Species reactivity	Staphylococcus aureus (P38507), Staphylococcus aureus (strain N315) (P99134), Staphylococcus aureus (strain Mu50 / ATCC 700699) (P0A015)
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a
Clone ID	SAA1452
Conjugation	APC
Clonality	Monoclonal
Target	spa, Immunoglobulin G-binding protein A, Staphylococcal protein A
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Accession	P38507
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Immunoglobulin G-binding protein A (SPA) is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), APC.pdf

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Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), APC (JN856137)

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