Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), PE (JN856127)

Name: Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), PE
Brand: abinScience
SKU: JN856127
Price: 256 USD
Availability: InStock

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Número de catálogo	JN856127
Reactividad de especies	Staphylococcus aureus
Aplicaciones	ELISA, FCM, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	SAA1452
Conjugación	PE
Objetivo	spa, Immunoglobulin G-binding protein A, Staphylococcal protein A
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PE
Número de acceso	P38507
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Immunoglobulin G-binding protein A (SPA) is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Staphylococcus aureus Protein A/SPA Recombinant Antibody (SAA1452), PE.pdf

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