

| Каталожный номер | JN856013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Staphylococcus aureus | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a | ||||
| ID клона | SAA1453 | ||||
| Цель | spa, Immunoglobulin G-binding protein A, Staphylococcal protein A | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P38507 | ||||
| RRID | Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1453) (abinScience Cat# JN856013, RRID:AB_3727082) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Immunoglobulin G-binding protein A (SPA) is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin. | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1453)




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