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Anti-SUMO1 Polyclonal Antibody (HX224014)

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Vista general
Número de catálogoHX224014
Descripción
Anti-SUMO1 Polyclonal Antibody (HX224014) is a rabbit polyclonal antibody detecting SUMO1 in ELISA, IHC, WB. Suitable for Bovine, Cervus nippon, Danio rerio, Chicken, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human SUMO1 (Met1-Val101).
Objetivo SUMO-1, SMT3C, SMT3H3, Sentrin, GMP1, Ubiquitin-like protein UBL1, UBL1, Small ubiquitin-related modifier 1, Ubiquitin-homology domain protein PIC1, SUMO1, Ubiquitin-like protein SMT3C, SMT3 homolog 3, Smt3C, GAP-modifying protein 1
Purificación Purified by antigen affinity column.
Número de acceso P63165
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Small ubiquitin-related modifier 1 (SUMO1) is a ~11 kDa protein. Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1.

1. Dai, XQ. et al. (2009) Journal of cell science 122, 775-9. PMID: 19223394
2. Sun, X. et al. (2014) PloS one 9, e92746. PMID: 24651376
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-SUMO1 Polyclonal Antibody

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