Anti-SUMO1 Polyclonal Antibody (HX224014)

Name: Anti-SUMO1 Polyclonal Antibody
Brand: abinScience
SKU: HX224014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HX224014

Description

Anti-SUMO1 Polyclonal Antibody (HX224014) is a rabbit polyclonal antibody detecting SUMO1 in ELISA, IHC, WB. Suitable for Bovine, Cervus nippon, Danio rerio, Chicken, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SUMO1 (Met1-Val101).

Cible

SUMO-1, SMT3C, SMT3H3, Sentrin, GMP1, Ubiquitin-like protein UBL1, UBL1, Small ubiquitin-related modifier 1, Ubiquitin-homology domain protein PIC1, SUMO1, Ubiquitin-like protein SMT3C, SMT3 homolog 3, Smt3C, GAP-modifying protein 1

Purification

Purified by antigen affinity column.

Numéro d'accès

P63165

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Small ubiquitin-related modifier 1 (SUMO1) is a ~11 kDa protein. Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1.

1. Dai, XQ. et al. (2009) Journal of cell science 122, 775-9. PMID: 19223394

2. Sun, X. et al. (2014) PloS one 9, e92746. PMID: 24651376

Note

For research use only.

Images

Reférences

Fiche technique

Anti-SUMO1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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