Anti-TOP2A Polyclonal Antibody (HY175024)

Name: Anti-TOP2A Polyclonal Antibody
Brand: abinScience
SKU: HY175024
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY175024

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human TOP2A (His54-Lys76).

Objetivo

DNA topoisomerase II, alpha isozyme, TOP2A, DNA topoisomerase 2-alpha, TOP2

Purificación

Purified by antigen affinity column.

Número de acceso

P11388

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

DNA topoisomerase 2-alpha (TOP2A) is a ~174 kDa protein. Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation.

1. Wyles, JP. et al. (2007) Nucleic acids research 35, 4076-85. PMID: 17567603

2. Williamson, EA. et al. (2008) Nucleic acids research 36, 5822-31. PMID: 18790802

3. Ramamoorthy, M. et al. (2012) Nucleic acids research 40, 1621-35. PMID: 22013166

4. Lee, S. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 2925-30. PMID: 22323612

5. Kratz, AS. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 3419-3431. PMID: 27754753

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-TOP2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo