Anti-TOP2A Polyclonal Antibody (HY175024)

Name: Anti-TOP2A Polyclonal Antibody
Brand: abinScience
SKU: HY175024
Price: 168 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HY175024

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human TOP2A (His54-Lys76).

Cible

DNA topoisomerase II, alpha isozyme, TOP2A, DNA topoisomerase 2-alpha, TOP2

Purification

Purified by antigen affinity column.

Numéro d'accès

P11388

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

DNA topoisomerase 2-alpha (TOP2A) is a ~174 kDa protein. Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation.

1. Wyles, JP. et al. (2007) Nucleic acids research 35, 4076-85. PMID: 17567603

2. Williamson, EA. et al. (2008) Nucleic acids research 36, 5822-31. PMID: 18790802

3. Ramamoorthy, M. et al. (2012) Nucleic acids research 40, 1621-35. PMID: 22013166

4. Lee, S. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 2925-30. PMID: 22323612

5. Kratz, AS. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 3419-3431. PMID: 27754753

Note

For research use only.

Images

Reférences

Fiche technique

Anti-TOP2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai