Anti-UBD Polyclonal Antibody (HT365014)

Name: Anti-UBD Polyclonal Antibody
Brand: abinScience
SKU: HT365014
Price: 168 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HT365014

Description

Anti-UBD Polyclonal Antibody (HT365014) is a rabbit polyclonal antibody detecting UBD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human UBD (Met1-Gly165).

Cible

Diubiquitin, UBD, Ubiquitin-like protein FAT10, Ubiquitin D, FAT10

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O15205

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Ubiquitin D (UBD) is a ~18 kDa protein. Ubiquitin-like protein modifier which can be covalently attached to target proteins and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Conjugation to the target protein is activated by UBA6 via adenylation of its C-terminal glycine. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs).

1. Hipp, MS. et al. (2005) Molecular and cellular biology 25, 3483-91. PMID: 15831455

2. Schmidtke, G. et al. (2006) The Journal of biological chemistry 281, 20045-54. PMID: 16707496

3. Schmidtke, G. et al. (2009) FEBS letters 583, 591-4. PMID: 19166848

4. Chiu, YH. et al. (2007) Molecular cell 27, 1014-23. PMID: 17889673

5. Truongvan, N. et al. (2022) Nature communications 13, 4789. PMID: 35970836

6. Gong, P. et al. (2010) Journal of the American Society of Nephrology : JASN 21, 316-26. PMID: 19959714

7. Ebstein, F. et al. (2009) The international journal of biochemistry & cell biology 41, 1205-15. PMID: 19028597

8. Ren, J. et al. (2006) The Journal of biological chemistry 281, 11413-21. PMID: 16495226

9. Kalveram, B. et al. (2008) Journal of cell science 121, 4079-88. PMID: 19033385

10. Ross, MJ. et al. (2006) Journal of the American Society of Nephrology : JASN 17, 996-1004. PMID: 16495380

Note

For research use only.

Images

Reférences

Fiche technique

Anti-UBD Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai