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| カタログ番号 | VK434013 |
|---|---|
| 種反応性 | Vesicular stomatitis Indiana virus (VSIV) |
| アプリケーション | FCM, IP, SPR |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | VHH-hFc |
| クローンID | 1004 |
| ターゲット | NP, Nucleoprotein, Nucleocapsid protein, Protein N |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P03521 |
| RRID | Anti-VSV NP/Nucleoprotein Antibody (1004) (abinScience Cat# VK434013, RRID:AB_3725342) |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Nucleoprotein (NP) is a ~47 kDa protein. Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. The nucleocapsid is bullet-shaped with the tip containing 8 turns of a conical spiral before reaching the helical cylindrical trunk. Nucleocapsid assembly is concomitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases. 1. Green, TJ. et al. (2006) Science (New York, N.Y.) 313, 357-60. PMID: 16778022 2. Ge, P. et al. (2010) Science (New York, N.Y.) 327, 689-93. PMID: 20133572 3. Gumpper, RH. et al. (2018) Journal of virology 92. PMID: 29437970 4. Jenni, S. et al. (2022) Nature communications 13, 4802. PMID: 35970826 5. Zhou, K. et al. (2022) Nature communications 13, 5980. PMID: 36216930 6. Green, TJ. et al. (2011) Journal of virology 85, 2714-22. PMID: 21177817 7. Si, Z. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2111948119. PMID: 35476516 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-VSV NP/Nucleoprotein Antibody (1004)
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