Anti-Vesicular stomatitis Indiana virus/VSIV NP/Nucleoprotein Recombinant Nanobody (SAA1125) (VK434053)

Name: Anti-Vesicular stomatitis Indiana virus/VSIV NP/Nucleoprotein Recombinant Nanobody (SAA1125)
Brand: abinScience
SKU: VK434053
Price: 191 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK434053

Description

Anti-Vesicular stomatitis Indiana virus/VSIV NP/Nucleoprotein Nanobody (SAA1125) [SAA1125] (VK434053) is a alpaca monoclonal antibody detecting Nucleoprotein in ELISA.

Species reactivity

Vesicular stomatitis Indiana virus (strain San Juan) (VSIV)

Applications

ELISA

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA1125

Clonality

Monoclonal

Target

Nucleoprotein, NP, Nucleocapsid protein, Protein N, N

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P03521

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Nucleoprotein (NP) is a ~47 kDa protein. Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. The nucleocapsid is bullet-shaped with the tip containing 8 turns of a conical spiral before reaching the helical cylindrical trunk. Nucleocapsid assembly is concomitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases.

1. Green, TJ. et al. (2006) Science (New York, N.Y.) 313, 357-60. PMID: 16778022

2. Ge, P. et al. (2010) Science (New York, N.Y.) 327, 689-93. PMID: 20133572

3. Gumpper, RH. et al. (2018) Journal of virology 92. PMID: 29437970

4. Jenni, S. et al. (2022) Nature communications 13, 4802. PMID: 35970826

5. Zhou, K. et al. (2022) Nature communications 13, 5980. PMID: 36216930

6. Green, TJ. et al. (2011) Journal of virology 85, 2714-22. PMID: 21177817

7. Si, Z. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2111948119. PMID: 35476516

Note

For research use only.

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