Anti-WDR5 Polyclonal Antibody (HX013014)

Name: Anti-WDR5 Polyclonal Antibody
Brand: abinScience
SKU: HX013014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HX013014

説明

Anti-WDR5 Polyclonal Antibody (HX013014) is a rabbit polyclonal antibody detecting WDR5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Xenopus tropicalis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human WDR5 (Met1-Lys120).

ターゲット

WDR5, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, BIG3

精製

Purified by antigen affinity column.

アクセッション番号

P61964

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

WD repeat-containing protein 5 (WDR5) is a ~36 kDa protein. Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.

1. Han, Z. et al. (2006) Molecular cell 22, 137-44. PMID: 16600877

2. Couture, JF. et al. (2006) Nature structural & molecular biology 13, 698-703. PMID: 16829960

3. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755

4. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338

5. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245

6. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852

7. Song, JJ. et al. (2008) The Journal of biological chemistry 283, 35258-64. PMID: 18840606

8. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120

9. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-WDR5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-WDR5 Polyclonal Antibody (HX013014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ