Anti-WDR5 Polyclonal Antibody (HX013014)

Name: Anti-WDR5 Polyclonal Antibody
Brand: abinScience
SKU: HX013014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HX013014

Описание

Anti-WDR5 Polyclonal Antibody (HX013014) is a rabbit polyclonal antibody detecting WDR5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Xenopus tropicalis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human WDR5 (Met1-Lys120).

Цель

WDR5, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, BIG3

Очистка

Purified by antigen affinity column.

Номер доступа

P61964

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

WD repeat-containing protein 5 (WDR5) is a ~36 kDa protein. Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.

1. Han, Z. et al. (2006) Molecular cell 22, 137-44. PMID: 16600877

2. Couture, JF. et al. (2006) Nature structural & molecular biology 13, 698-703. PMID: 16829960

3. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755

4. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338

5. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245

6. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852

7. Song, JJ. et al. (2008) The Journal of biological chemistry 283, 35258-64. PMID: 18840606

8. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120

9. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-WDR5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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