

| Número de catálogo | JN845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014) is a rabbit polyclonal antibody detecting Aed a 2 in ELISA, IHC, WB. Suitable for Aedes aegypti.
Highlights
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| Reactividad de especies | Aedes aegypti (Yellowfever mosquito) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Yellowfever mosquito Aed a 2/AeD7L1 (Ser18-Gln321). | ||||||||
| Objetivo | Long form salivary protein D7L1, AeD7, AeD7L1, 37 kDa salivary gland allergen Aed a 2, Protein D7, Aed a 2, D7, D7L1, AAEL006424, Aed a 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P18153 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Long form salivary protein D7L1 (Aed a 2/AeD7L1) is a ~36 kDa protein. Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response, such as biogenic amines and eicosanoids. Binds serotonin, histamine, leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4, adrenaline and noradrenaline. Does not bind tryptamine and U-46619, a stable analog of thromboxane A2. Exhibits vasodilating activity. Inhibits agonist-induced platelet aggregation but not blood clotting. 1. Martin-Martin, I. et al. (2021) The FEBS journal 288, 2014-2029. PMID: 32799410 2. Martin-Martin, I. et al. (2023) mBio 14, e0228923. PMID: 37909749 3. Calvo, E. et al. (2006) The Journal of biological chemistry 281, 1935-42. PMID: 16301315 4. Calvo, E. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 3728-33. PMID: 19234127 | ||||||||
| Nota | For research use only. |
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