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Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014)

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概要
カタログ番号JN845014
説明
Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014) is a rabbit polyclonal antibody detecting Aed a 2 in ELISA, IHC, WB. Suitable for Aedes aegypti.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Aedes aegypti (Yellowfever mosquito)
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Yellowfever mosquito Aed a 2/AeD7L1 (Ser18-Gln321).
ターゲット Long form salivary protein D7L1, AeD7, AeD7L1, 37 kDa salivary gland allergen Aed a 2, Protein D7, Aed a 2, D7, D7L1, AAEL006424, Aed a 2
精製 Purified by antigen affinity column.
アクセッション番号 P18153
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Long form salivary protein D7L1 (Aed a 2/AeD7L1) is a ~36 kDa protein. Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response, such as biogenic amines and eicosanoids. Binds serotonin, histamine, leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4, adrenaline and noradrenaline. Does not bind tryptamine and U-46619, a stable analog of thromboxane A2. Exhibits vasodilating activity. Inhibits agonist-induced platelet aggregation but not blood clotting.

1. Martin-Martin, I. et al. (2021) The FEBS journal 288, 2014-2029. PMID: 32799410
2. Martin-Martin, I. et al. (2023) mBio 14, e0228923. PMID: 37909749
3. Calvo, E. et al. (2006) The Journal of biological chemistry 281, 1935-42. PMID: 16301315
4. Calvo, E. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 3728-33. PMID: 19234127
注意事項 For research use only.
イメージ
参考文献
Formula
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