

| Каталожный номер | HV070014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-ZG16B Polyclonal Antibody (HV070014) is a rabbit polyclonal antibody detecting ZG16B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human ZG16B (Gly53-Arg208). | ||||||||
| Цель | Zymogen granule protein 16 homolog B, ZG16B | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q96DA0 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Pancreatic adenocarcinoma up-regulated factor (ZG16B) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway. 1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558 2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292 3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-ZG16B polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human ZG16B (Catalog No: HV070012)



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