Anti-Human PAUF Reference Antibody (Ulenistamab, RUO) (HB774016)

Name: Anti-Human PAUF Reference Antibody (Ulenistamab, RUO)
Brand: abinScience
SKU: HB774016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB774016
Description	Ulenistamab (HB774016) is a research-grade recombinant antibody targeting PAUF. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	PAUF
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96DA0
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	PBP1510, PBP-1510, PBP15102415259-90-2
Background	Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway. 1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558 2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292 3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715
Note	For research use only. Not suitable for clinical or therapeutic use.