Anti-ZG16B Polyclonal Antibody (HV070014)

Name: Anti-ZG16B Polyclonal Antibody
Brand: abinScience
SKU: HV070014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV070014

Description

Anti-ZG16B Polyclonal Antibody (HV070014) is a rabbit polyclonal antibody detecting ZG16B in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ZG16B (Gly53-Arg208).

Target

Zymogen granule protein 16 homolog B, ZG16B

Purification

Purified by antigen affinity column.

Accession

Q96DA0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Pancreatic adenocarcinoma up-regulated factor (ZG16B) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway.

1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558

2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292

3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ZG16B polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human ZG16B (Catalog No: HV070012)

References

Datasheet