

| Numéro de catalogue | DB691018 |
|---|---|
| Description |
Daratumumab ELISA Kit (DB691018) — Quantitative sandwich ELISA for Daratumumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL. Sensitivity: 104.76 ng/mL.
Highlights
|
| Type d'échantillon | Plasma, Serum |
| Sensibilité | 104.76 ng/mL |
| Plage | 156.25 - 10, 000 ng/mL |
| Numéro d'accès | P28907 |
| Applications | ELISA |
| Méthode de détection | Colorimetric |
| Type de test | Quantitative |
| Retraitement | 80-120% |
| Expédition | 2-8 ℃ |
| Stabilité et stockage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20 ℃, the rest reagents should be store at 4℃. |
| Spécifications | Daratumumab |
| Noms alternatifs | HuMax-CD38, 945721-28-8 |
| Contexte | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (Daratumumab) is a ~34 kDa protein. Multifunctional transmembrane glycoprotein able to exert enzymatic activities and also to mobilize calcium, to transduce signals, to adhere to hyaluronan and to other ligands. Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. 1. Tohgo, A. et al. (1994) The Journal of biological chemistry 269, 28555-7. PMID: 7961800 2. Takasawa, S. et al. (1993) The Journal of biological chemistry 268, 26052-4. PMID: 8253715 3. Moreschi, I. et al. (2006) Biochemical and biophysical research communications 345, 573-80. PMID: 16690024 4. Deaglio, S. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 395-402. PMID: 9551996 5. Frasca, L. et al. (2006) Blood 107, 2392-9. PMID: 16293598 6. Deaglio, S. et al. (2001) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 15, 580-2. PMID: 11259373 |
| Note | For Research Use Only. |

Standard Curve of Daratumumab ELISA Kit




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