Emactuzumab ELISA Kit (DY035028)

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Número de catálogo	DY035028
Descripción	Emactuzumab ELISA Kit (DY035028) — Quantitative sandwich ELISA for Emactuzumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml. Highlights ●Sandwich Format — High specificity, reliable quantification. ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with pre-coated plates included.
Tipo de muestra	Plasma, Serum
Sensibilidad	0.156 μg/ml
Rango	0.31-5 μg/mL
Número de acceso	P07333
Aplicaciones	ELISA
Método de detección	Colorimetric
Tipo de ensayo	Quantitative
Recuperación	80-120%
Envío	2-8 ℃
Estabilidad y almacenamiento	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Especificaciones	Emactuzumab
Nombres alternativos	RG 7155, RO5509554, 1448221-67-7
Fondo	Macrophage colony-stimulating factor 1 receptor (Emactuzumab) is a ~107 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. 1. Wei, S. et al. (2010) Journal of leukocyte biology 88, 495-505. PMID: 20504948 2. Guo, L. et al. (2019) American journal of human genetics 104, 925-935. PMID: 30982609 3. Oosterhof, N. et al. (2019) American journal of human genetics 104, 936-947. PMID: 30982608
Nota	For Research Use Only.