HEK293T Human VTCN1/B7-H4 Stable Cell Line (HV721818)

Обзор

Каталожный номер	HV721818
Описание	HEK293T Human VTCN1/B7-H4 Stable Cell Line (HV721818) is a stable cell line expressing VTCN1/B7-H4. Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
Номер доступа	Q7Z7D3
Применения	FCM
Хозяинский вид	HEK293T
Виды	Human
Цель	VTCN1/B7-H4
Свойства	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
Устойчивость и хранение	Frozen in liquid nitrogen.
Характеристики	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
Фон	V-set domain-containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Изображения

Flow cytometry

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human B7H4 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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