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| カタログ番号 | VK672818 |
|---|---|
| 説明 |
HEK293T SARS-CoV-2 Envelope small membrane protein (E) Stable Cell Line (VK672818) is a stable cell line expressing SARS-CoV-2 Envelope small membrane protein (E). Engineered for consistent, high-level target expression in research applications.
Highlights
|
| アクセッション番号 | P0DTC4 |
| アプリケーション | FCM |
| 宿主種 | HEK293T |
| 種 | Viral (SARS-CoV-2) |
| ターゲット | SARS-CoV-2 Envelope small membrane protein (E) |
| 特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 安定性と保存 | Frozen in liquid nitrogen. |
| 仕様 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | Envelope small membrane protein (SARS-CoV-2 Envelope small membrane protein (E)) is a ~8 kDa protein. Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Regulates the localization of S protein at cis-Golgi, the place of virus budding. May act by slowing down the cell secretory pathway. 1. Boson, B. et al. (2021) The Journal of biological chemistry 296, 100111. PMID: 33229438 2. De Maio, F. et al. (2020) Microbes and infection 22, 592-597. PMID: 32891874 |
Untransfected cells and Transfected cells were tested with qPCR.
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