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| カタログ番号 | MF998109 |
|---|---|
| 説明 |
InVivo Plus Anti-Mouse CD4 Antibody (GK1.5) [GK1.5] (MF998109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD4 in in vivo CD4+ T cell depletion, FCM, WB. Suitable for Mouse.
Highlights
|
| 種反応性 | Mouse |
| アプリケーション | in vivo CD4+ T cell depletion, FCM, WB |
| 宿主種 | Rat |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2b |
| クローンID | GK1.5 |
| ターゲット | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| エンドトキシンレベル | < 1 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P06332 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)
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