InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (VK589050)

Name: InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19)
Brand: abinScience
SKU: VK589050
Price: 370 USD
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100ug
1mg

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Número de catálogo	VK589050
Descripción	InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) [1C19] (VK589050) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Reactividad de especies	Dengue virus 1 (DENV-1), Dengue virus 2 (DENV-2), Dengue virus 3 (DENV-3), Dengue virus 4 (DENV-4)
Aplicaciones	ELISA, Neutralization
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	1C19
Objetivo	Envelope protein E
Nivel de endotoxinas	< 1 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. 1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341 2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804 3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430 4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008
Nota	For research use only. Not suitable for clinical or therapeutic use.