中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | VK589050 |
|---|---|
| 説明 |
InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) [1C19] (VK589050) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
|
| 種反応性 | Dengue virus 1 (DENV-1), Dengue virus 2 (DENV-2), Dengue virus 3 (DENV-3), Dengue virus 4 (DENV-4) |
| アプリケーション | ELISA, Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | 1C19 |
| ターゲット | Envelope protein E |
| エンドトキシンレベル | < 1 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. 1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341 2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804 3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430 4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
