InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (VK589050)

Name: InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19)
Brand: abinScience
SKU: VK589050
Price: 370 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	VK589050
Описание	InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) [1C19] (VK589050) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Реактивность видов	Dengue virus 1 (DENV-1), Dengue virus 2 (DENV-2), Dengue virus 3 (DENV-3), Dengue virus 4 (DENV-4)
Применения	ELISA, Neutralization
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	1C19
Цель	Envelope protein E
Уровень эндотоксинов	< 1 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Связанные продукты	pH 7.4 Dilution Buffer
Очистка	Protein A/G purified from cell culture supernatant.
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. 1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341 2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804 3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430 4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008
Примечание	For research use only. Not suitable for clinical or therapeutic use.