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| カタログ番号 | JN822010 |
|---|---|
| 説明 |
InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#) [11E10#] (JN822010) is a human monoclonal antibody detecting rRNA N-glycosylase in ELISA, Neutralization. Suitable for Escherichia coli.
|
| 種反応性 | Escherichia coli |
| アプリケーション | ELISA, Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | 11E10# |
| ターゲット | rRNA N-glycosylase, 3.2.2.22, stx2 A-subunit, stx-2 A subunit, stx2, stx2A, stx2a, stx2A_1, stx2cA, stx2vA, stxA2, stxA_1, stxA_3, vta, vtx2A, Escherichia coli |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P09385 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Shiga-like toxin 2 subunit A (shiga toxin type 2A/stx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-Escherichia coli shiga toxin type 2/stx2A Antibody (11E10#).
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