Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

Name: Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)
Brand: abinScience
SKU: JN822016
Price: 176 USD
Availability: InStock

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SDS

Overview

Catalog No.	JN822016
Description	Setoxaximab (JN822016) is a research-grade recombinant antibody targeting shiga toxin type 2stx2A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Escherichia coli
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Chimeric
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	shiga toxin type 2stx2A
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P09385
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Shigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx2, 1351470-17-1
Background	Shiga-like toxin 2 subunit A (shiga toxin type 2Astx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Setoxaximab.
SDS-PAGE

SDS-PAGE for Research Grade Setoxaximab

References

Datasheet

Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO).pdf

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Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

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Datasheet

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