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| カタログ番号 | VK646030 | ||||
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| 説明 |
InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0261) [Iv0261] (VK646030) is a human monoclonal antibody detecting Envelopment polyprotein in ELISA, Neutralization. Suitable for Seoul virus (SEOV) and Andes virus (ANDV).
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| 種反応性 | Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Orthohantavirus puumalaense (Puumala virus) (PUUV), Dobrava-Belgrade virus (DOBV), Seoul virus (SEOV), Andes virus (Andes orthohantavirus), Sin Nombre virus (SNV) | ||||
| アプリケーション | ELISA, Neutralization | ||||
| 宿主種 | Human | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1 | ||||
| クローンID | Iv0261 | ||||
| ターゲット | Envelopment polyprotein, M polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 関連製品 | pH 7.4 Dilution Buffer | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q89905 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif. | ||||
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0261)
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